Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity.

The androgen receptor (AR) is a steroid-activated transcription factor that binds at specific DNA locations and plays a key role in the etiology of prostate cancer. While numerous studies have identified a clear connection between AR binding and expression of target genes for a limited number of loc...

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Bibliographic Details
Main Authors: Li Jia, Benjamin P Berman, Unnati Jariwala, Xiting Yan, Jon P Cogan, Allison Walters, Ting Chen, Grant Buchanan, Baruch Frenkel, Gerhard A Coetzee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2577007?pdf=render