Algorithmically Deduced <i>FREM2</i> Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas

Algorithmically Deduced <i>FREM2</i> Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas

Gliomas are the most common malignant brain tumors with high mortality rates. Recently we showed that the <i>FREM2</i> gene has a role in glioblastoma progression. Here we reconstructed the <i>FREM2</i> molecular pathway using the human interactome model. We assessed the biom...

Full description

Bibliographic Details
Main Authors: Marianna Zolotovskaia, Victor Tkachev, Maxim Sorokin, Andrew Garazha, Ella Kim, Sven Rainer Kantelhardt, Sven-Ernö Bikar, Alja Zottel, Neja Šamec, Denis Kuzmin, Bettina Sprang, Alexey Moisseev, Alf Giese, Victor Efimov, Ivana Jovčevska, Anton Buzdin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
<i>FREM2</i>
glioma
glioblastoma
survival prognosis
algorithmically deduced molecular pathway
transcriptomics
Online Access:https://www.mdpi.com/2072-6694/13/16/4117

Internet

https://www.mdpi.com/2072-6694/13/16/4117

Similar Items