The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancerResearch in context

The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancerResearch in context

Background: Comprehensive transcriptomic analyses have shown that colorectal cancer (CRC) is heterogeneous and have led to the definition of molecular subtypes among which the stem-cell, mesenchymal-like group is associated with poor prognosis. The molecular pathways orchestrating the emergence of t...

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Main Authors: Delphine Le Corre, Alexandre Ghazi, Ralyath Balogoun, Camilla Pilati, Thomas Aparicio, Séverine Martin-Lannerée, Laetitia Marisa, Fatima Djouadi, Virginie Poindessous, Carole Crozet, Jean-François Emile, Claire Mulot, Karine Le Malicot, Valérie Boige, Hélène Blons, Aurélien de Reynies, Julien Taieb, François Ghiringhelli, Jaafar Bennouna, Jean-Marie Launay, Pierre Laurent-Puig, Sophie Mouillet-Richard
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304785

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http://www.sciencedirect.com/science/article/pii/S2352396419304785

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