Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.

BACKGROUND:Although several studies suggest that genetic factors are associated with human UTI susceptibility, the role of DNA variation in regulating early in vivo urine inflammatory responses has not been fully examined. We examined whether candidate gene polymorphisms were associated with altered...

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Bibliographic Details
Main Authors: Thomas R Hawn, Delia Scholes, Hongwei Wang, Sue S Li, Ann E Stapleton, Marta Janer, Alan Aderem, Walter E Stamm, Lue Ping Zhao, Thomas M Hooton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2788705?pdf=render