Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

Emergency myelopoiesis is inflammation-induced hematopoiesis to replenish myeloid cells in the periphery, which is critical to control the infection with pathogens. Previously, pro-inflammatory cytokines such as interferon (IFN)-α and IFN-γ were demonstrated to play a critical role in the expansion...

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Bibliographic Details
Main Authors: Jun-ichi Furusawa, Izuru Mizoguchi, Yukino Chiba, Masayuki Hisada, Fumie Kobayashi, Hiroki Yoshida, Susumu Nakae, Akihiko Tsuchida, Tetsuya Matsumoto, Hideo Ema, Junichiro Mizuguchi, Takayuki Yoshimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4798290?pdf=render

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http://europepmc.org/articles/PMC4798290?pdf=render

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