Stability and Heterogeneity of Expression Profiles in Lung Cancer Specimens Harvested Following Surgical Resection

Stability and Heterogeneity of Expression Profiles in Lung Cancer Specimens Harvested Following Surgical Resection

One of the major concerns in microarray profiling studies of clinical samples is the effect of tissue sampling and RNA extraction on data. We analyzed gene expression in lung cancer specimens that were serially harvested from tumor mass and snap-frozen at several intervals up to 120 minutes after s...

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Bibliographic Details
Main Authors: Fiona H. Blackhall, Melania Pintilie, Dennis A. Wigle, Igor Jurisica, Ni Liu, Nikolina Radulovich, Michael R. Johnston, Shaf Keshavjee, Ming-Sound Tsao
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Lung cancer
microarray
real-time RT-PCR
tumor heterogeneity
surgical specimen
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800083

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http://www.sciencedirect.com/science/article/pii/S1476558604800083

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