Convergent evolution and topologically disruptive polymorphisms among multidrug-resistant tuberculosis in Peru.

<h4>Background</h4>Multidrug-resistant tuberculosis poses a major threat to the success of tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis evolves can inform the development of new therapeutic and preventive strategies.<h4>Methods</h4>He...

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Bibliographic Details
Main Authors: Louis Grandjean, Robert H Gilman, Tomatada Iwamoto, Claudio U Köser, Jorge Coronel, Mirko Zimic, M Estee Török, Diepreye Ayabina, Michelle Kendall, Christophe Fraser, Simon Harris, Julian Parkhill, Sharon J Peacock, David A J Moore, Caroline Colijn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0189838