Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase
Abstract The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing haplotypes, and mapping methylation...
Main Authors: | Vahid Akbari, Jean-Michel Garant, Kieran O’Neill, Pawan Pandoh, Richard Moore, Marco A. Marra, Martin Hirst, Steven J. M. Jones |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-021-02283-5 |
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