Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells.

Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells.

Metformin has been widely used as an oral drug for diabetes mellitus for approximately 60 years. Interestingly, recent reports showed that metformin exhibited an anti-tumor action in a wide range of malignancies including hepatocellular carcinoma (HCC). In the present study, we investigated its impa...

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Bibliographic Details
Main Authors: Tomoko Saito, Tetsuhiro Chiba, Kaori Yuki, Yoh Zen, Motohiko Oshima, Shuhei Koide, Tenyu Motoyama, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Akinobu Tawada, Motohisa Tada, Fumihiko Kanai, Yuichi Takiguchi, Atsushi Iwama, Osamu Yokosuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726625?pdf=render

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http://europepmc.org/articles/PMC3726625?pdf=render

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