Novel myocardial markers GADD45G and NDUFS5 identified by RNA-sequencing predicts left ventricular reverse remodeling in advanced non-ischemic heart failure: a retrospective cohort...

by Togo Iwahana, Sho Okada, Masato Kanda, Motohiko Oshima, Atsushi Iwama, Goro Matsumiya, Yoshio Kobayashi
Published 2020-03-01

Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription

by Yumiko Oishi, Shinichiro Hayashi, Takayuki Isagawa, Motohiko Oshima, Atsushi Iwama, Shigeki Shimba, Hitoshi Okamura, Ichiro Manabe
Published 2017-08-01

Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus

by Atsushi Okabe, Sayaka Funata, Keisuke Matsusaka, Hiroe Namba, Masaki Fukuyo, Bahityar Rahmutulla, Motohiko Oshima, Atsushi Iwama, Masashi Fukayama, Atsushi Kaneda
Published 2017-08-01

Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells.

by Sha Si, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Motohiko Oshima, Atsunori Saraya, Hiroki Sugishita, Manabu Nakayama, Tomoyuki Ishikura, Haruhiko Koseki, Atsushi Iwama
Published 2016-01-01

Bmi1 confers resistance to oxidative stress on hematopoietic stem cells.

by Shunsuke Nakamura, Motohiko Oshima, Jin Yuan, Atsunori Saraya, Satoru Miyagi, Takaaki Konuma, Satoshi Yamazaki, Mitsujiro Osawa, Hiromitsu Nakauchi, Haruhiko Koseki, Atsushi Iwama
Published 2012-01-01

Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.

by Changshan Wang, Motohiko Oshima, Goro Sashida, Takahisa Tomioka, Nagisa Hasegawa, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi, Atsushi Iwama
Published 2015-01-01

Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome

by Kazumasa Aoyama, Motohiko Oshima, Shuhei Koide, Emi Suzuki, Makiko Mochizuki-Kashio, Yuko Kato, Shiro Tara, Daisuke Shinoda, Nobuhiro Hiura, Yaeko Nakajima-Takagi, Goro Sashida, Atsushi Iwama
Published 2018-11-01

The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells

by Satoru Miyagi, Shuhei Koide, Atsunori Saraya, George R. Wendt, Motohiko Oshima, Takaaki Konuma, Satoshi Yamazaki, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Changshan Wang, Tetsuhiro Chiba, Issay Kitabayashi, Hiromitsu Nakauchi, Atsushi Iwama
Published 2014-02-01

Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells.

by Tomoko Saito, Tetsuhiro Chiba, Kaori Yuki, Yoh Zen, Motohiko Oshima, Shuhei Koide, Tenyu Motoyama, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Akinobu Tawada, Motohisa Tada, Fumihiko Kanai, Yuichi Takiguchi, Atsushi Iwama, Osamu Yokosuka
Published 2013-01-01

Genome-Wide Mapping of Bivalent Histone Modifications in Hepatic Stem/Progenitor Cells

by Kengo Kanayama, Tetsuhiro Chiba, Motohiko Oshima, Hiroaki Kanzaki, Shuhei Koide, Atsunori Saraya, Satoru Miyagi, Naoya Mimura, Yuko Kusakabe, Tomoko Saito, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Hitoshi Maruyama, Atsushi Iwama, Naoya Kato
Published 2019-01-01

Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm

by Sho Kubota, Kenji Tokunaga, Tomohiro Umezu, Takako Yokomizo-Nakano, Yuqi Sun, Motohiko Oshima, Kar Tong Tan, Henry Yang, Akinori Kanai, Eisaku Iwanaga, Norio Asou, Takahiro Maeda, Naomi Nakagata, Atsushi Iwama, Kazuma Ohyashiki, Motomi Osato, Goro Sashida
Published 2019-04-01

Author Correction: Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm

by Sho Kubota, Kenji Tokunaga, Tomohiro Umezu, Takako Yokomizo-Nakano, Yuqi Sun, Motohiko Oshima, Kar Tong Tan, Henry Yang, Akinori Kanai, Eisaku Iwanaga, Norio Asou, Takahiro Maeda, Naomi Nakagata, Atsushi Iwama, Kazuma Ohyashiki, Motomi Osato, Goro Sashida
Published 2019-08-01

Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent manners.

by Tetsuhiro Chiba, Eiichiro Suzuki, Kaori Yuki, Yoh Zen, Motohiko Oshima, Satoru Miyagi, Atsunori Saraya, Shuhei Koide, Tenyu Motoyama, Sadahisa Ogasawara, Yoshihiko Ooka, Akinobu Tawada, Tetsuya Nakatsura, Takehiro Hayashi, Taro Yamashita, Syuichi Kaneko, Masaru Miyazaki, Atsushi Iwama, Osamu Yokosuka
Published 2014-01-01

The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells

by Yurie Nagai, Naoya Mimura, Ola Rizq, Yusuke Isshiki, Motohiko Oshima, Mohamed Rizk, Atsunori Saraya, Shuhei Koide, Yaeko Nakajima-Takagi, Makiko Miyota, Tetsuhiro Chiba, Nagisa Oshima-Hasegawa, Tomoya Muto, Shokichi Tsukamoto, Shio Mitsukawa, Yusuke Takeda, Chikako Ohwada, Masahiro Takeuchi, Tohru Iseki, Chiaki Nakaseko, William Lennox, Josephine Sheedy, Marla Weetall, Koutaro Yokote, Atsushi Iwama, Emiko Sakaida
Published 2021-01-01