A Carotenoid Extract from a Southern Italian Cultivar of Pumpkin Triggers Nonprotective Autophagy in Malignant Cells

Carotenoids, including β-carotene, lycopene, and derivatives, such as retinoic acid, have been studied for their significant antiproliferative and differentiating activity on cancer cells in experimental models and in clinics. We are presenting here data on the mechanism of action of a carotenoid-en...

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Main Authors: Maria Russo, Stefania Moccia, Stefania Bilotto, Carmela Spagnuolo, Miriana Durante, Marcello Salvatore Lenucci, Giovanni Mita, Maria Grazia Volpe, Rita Patrizia Aquino, Gian Luigi Russo
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/7468538