Alignment and mapping methodology influence transcript abundance estimation

Alignment and mapping methodology influence transcript abundance estimation

Abstract Background The accuracy of transcript quantification using RNA-seq data depends on many factors, such as the choice of alignment or mapping method and the quantification model being adopted. While the choice of quantification model has been shown to be important, considerably less attention...

Full description

Bibliographic Details
Main Authors: Avi Srivastava, Laraib Malik, Hirak Sarkar, Mohsen Zakeri, Fatemeh Almodaresi, Charlotte Soneson, Michael I. Love, Carl Kingsford, Rob Patro
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Genome Biology
Subjects:
RNA-seq
Read-alignment
Quantification
Online Access:http://link.springer.com/article/10.1186/s13059-020-02151-8

Internet

http://link.springer.com/article/10.1186/s13059-020-02151-8

Similar Items