Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol

Oxysterols are known pleiotropic molecules whose antiviral action has been recently discovered. Here reported is the activity of a panel of oxysterols against HSV-1 with the identification of a new mechanism of action. A marked antiviral activity not only of 25HC but also of 27HC against HSV-1 was o...

Full description

Bibliographic Details
Main Authors: Valeria Cagno, Andrea Civra, Daniela Rossin, Simone Calfapietra, Claudio Caccia, Valerio Leoni, Nicholas Dorma, Fiorella Biasi, Giuseppe Poli, David Lembo
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717301659