VSL#3 resets insulin signaling and protects against NASH and atherosclerosis in a model of genetic dyslipidemia and intestinal inflammation.

BACKGROUND: Signals generated by the inflammed intestine are thought to contribute to metabolic derangement. The intestinal microbiota contributes to instructing the immune system beyond the intestinal wall and its modulation is a potential target for treating systemic disorders. AIMS: To investigat...

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Bibliographic Details
Main Authors: Andrea Mencarelli, Sabrina Cipriani, Barbara Renga, Angela Bruno, Claudio D'Amore, Eleonora Distrutti, Stefano Fiorucci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448636?pdf=render