A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

Abstract Background Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack of frank neuropathology from models based on common disease genes. Recent multi-cohort studies of post...

Full description

Bibliographic Details
Main Authors: Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, the MODEL-AD Consortium, Gregory W. Carter
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s13024-020-00412-5

Internet

http://link.springer.com/article/10.1186/s13024-020-00412-5

Similar Items