Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Atherosclerosis stems from imbalances in lipid metabolism and leads to maladaptive inflammatory responses. The AMP-activated protein kinase (Ampk) is a highly conserved serine/threonine kinase that regulates many aspects of lipid and energy metabolism, although its specific role in controlling macro...

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Bibliographic Details
Main Authors: Morgan D. Fullerton, Rebecca J. Ford, Chelsea P. McGregor, Nicholas D. LeBlond, Shayne A. Snider, Stephanie A. Stypa, Emily A. Day, Šárka Lhoták, Jonathan D. Schertzer, Richard C. Austin, Bruce E. Kemp, Gregory R. Steinberg
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Journal of Lipid Research
Subjects:
cholesterol efflux
adenosine 5′-monophosphate-activated protein kinase
lipid homeostasis
atherosclerosis
reverse cholesterol transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520312426

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http://www.sciencedirect.com/science/article/pii/S0022227520312426

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