Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency

The reason why HIV cannot be cured by current therapy is because of viral persistence in resting T cells. One approach to permanent HIV remission that has received less attention is the so-called “block and lock” approach. The idea behind this approach is that the virus could be permanently disabled...

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Bibliographic Details
Main Authors: George B. Kyei, Shanshan Meng, Rashmi Ramani, Austin Niu, Chandraiah Lagisetti, Thomas R. Webb, Lee Ratner
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01423-18