Correction for both common and rare cell types in blood is important to identify genes that correlate with age

Correction for both common and rare cell types in blood is important to identify genes that correlate with age

Abstract Background Aging is a multifactorial process that affects multiple tissues and is characterized by changes in homeostasis over time, leading to increased morbidity. Whole blood gene expression signatures have been associated with aging and have been used to gain information on its biologica...

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Bibliographic Details
Main Authors: Damiano Pellegrino-Coppola, Annique Claringbould, Maartje Stutvoet, BIOS Consortium, Dorret I. Boomsma, M. Arfan Ikram, P. Eline Slagboom, Harm-Jan Westra, Lude Franke
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Genomics
Subjects:
Whole blood
Gene expression
Cell counts correction
Aging
Platelet activity
Online Access:https://doi.org/10.1186/s12864-020-07344-w

Internet

https://doi.org/10.1186/s12864-020-07344-w

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