IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

IgE contributes to host-protective functions in parasitic and bacterial infections, often by monocyte and macrophage recruitment. We previously reported that monocytes contribute to tumour antigen-specific IgE-mediated tumour growth restriction in rodent models. Here, we investigate the impact of Ig...

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Bibliographic Details
Main Authors: Mano Nakamura, Elmira Amiri Souri, Gabriel Osborn, Roman Laddach, Jitesh Chauhan, Chara Stavraka, Sara Lombardi, Anna Black, Atousa Khiabany, Duaa O. Khair, Mariangela Figini, Anna Winship, Sharmistha Ghosh, Ana Montes, James F. Spicer, Heather J. Bax, Debra H. Josephs, Katie E. Lacy, Sophia Tsoka, Sophia N. Karagiannis
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
IgE
Online Access:https://www.mdpi.com/2072-6694/12/11/3376