Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

Hypertension is a major health problem of largely unknown genetic origins. To identify new genes responsible for hypertension, genetic analysis of recombinant inbred strains of mice followed by human association studies might prove powerful and was exploited in our current study. Using a set of 27 r...

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Bibliographic Details
Main Authors: Hana Koutnikova, Markku Laakso, Lu Lu, Roy Combe, Jussi Paananen, Teemu Kuulasmaa, Johanna Kuusisto, Hans-Ulrich Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markolf Hanefeld, Robert W Williams, Johan Auwerx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2715105?pdf=render

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http://europepmc.org/articles/PMC2715105?pdf=render

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