Differential induction of TLR3-dependent innate immune signaling by closely related parasite species.

Differential induction of TLR3-dependent innate immune signaling by closely related parasite species.

The closely related protozoan parasites Toxoplasma gondii and Neospora caninum display similar life cycles, subcellular ultrastructure, invasion mechanisms, metabolic pathways, and genome organization, but differ in their host range and disease pathogenesis. Type II (γ) interferon has long been know...

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Bibliographic Details
Main Authors: Daniel P Beiting, Lucia Peixoto, Natalia S Akopyants, Stephen M Beverley, E John Wherry, David A Christian, Christopher A Hunter, Igor E Brodsky, David S Roos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914978?pdf=render

Internet

http://europepmc.org/articles/PMC3914978?pdf=render

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