5-(3′,4′-Dihydroxyphenyl)-γ-valerolactone and its sulphate conjugates, representative circulating metabolites of flavan-3-ols, exhibit anti-adhesive activity against uropathogenic Escherichia coli in bladder epithelial cells

5-(3′,4′-Dihydroxyphenyl)-γ-valerolactone and its sulphate conjugates, representative circulating metabolites of flavan-3-ols, exhibit anti-adhesive activity against uropathogenic Escherichia coli in bladder epithelial cells

Urinary tract infections (UTI) are mostly caused by uropathogenic Escherichia coli (UPEC). Cranberry-based products have shown preventive effects against UTI, and this has been partially attributed to their A-type proanthocyanidin content. However, recent evidence reports phenyl-γ-valerolactones as...

Full description

Bibliographic Details
Main Authors: Pedro Mena, Dolores González de Llano, Nicoletta Brindani, Adelaida Esteban-Fernández, Claudio Curti, María Victoria Moreno-Arribas, Daniele Del Rio, Begoña Bartolomé
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Journal of Functional Foods
Subjects:
Phenyl-γ-valerolactone
Flavan-3-ol metabolite
UPEC
Peripheral metabolism
Cranberry
Urinary tract infections
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616304340

Internet

http://www.sciencedirect.com/science/article/pii/S1756464616304340

Similar Items