10,12 Conjugated Linoleic Acid-Driven Weight Loss Is Protective against Atherosclerosis in Mice and Is Associated with Alternative Macrophage Enrichment in Perivascular Adipose Tissue

10,12 Conjugated Linoleic Acid-Driven Weight Loss Is Protective against Atherosclerosis in Mice and Is Associated with Alternative Macrophage Enrichment in Perivascular Adipose Tissue

The dietary fatty acid 10,12 conjugated linoleic acid (10,12 CLA) promotes weight loss by increasing fat oxidation, but its effects on atherosclerosis are less clear. We recently showed that weight loss induced by 10,12 CLA in an atherosclerosis-susceptible mouse model with characteristics similar t...

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Bibliographic Details
Main Authors: Jenny E. Kanter, Leela Goodspeed, Shari Wang, Farah Kramer, Tomasz Wietecha, Diego Gomes-Kjerulf, Savitha Subramanian, Kevin D. O’Brien, Laura J. den Hartigh
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Nutrients
Subjects:
alternatively activated macrophages
perivascular adipose tissue
type 2 cytokines
Online Access:http://www.mdpi.com/2072-6643/10/10/1416

Internet

http://www.mdpi.com/2072-6643/10/10/1416

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