Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.

Successful control of falciparum malaria depends greatly on treatment with artemisinin combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged, and that the prevalence of this resistance is increasing, are alarming. ART resistance has recently been linked to mutations...

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Bibliographic Details
Main Authors: Con Dogovski, Stanley C Xie, Gaetan Burgio, Jess Bridgford, Sachel Mok, James M McCaw, Kesinee Chotivanich, Shannon Kenny, Nina Gnädig, Judith Straimer, Zbynek Bozdech, David A Fidock, Julie A Simpson, Arjen M Dondorp, Simon Foote, Nectarios Klonis, Leann Tilley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002132

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https://doi.org/10.1371/journal.pbio.1002132

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