Autosomal recessive osteopetrosis: mechanisms and treatments

Autosomal recessive osteopetrosis (ARO) is a severe inherited bone disease characterized by defective osteoclast resorption or differentiation. Clinical manifestations include dense and brittle bones, anemia and progressive nerve compression, which hamper the quality of patients' lives and caus...

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Bibliographic Details
Main Authors: Sara Penna, Anna Villa, Valentina Capo
Format: Article
Language:English
Published: The Company of Biologists 2021-05-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/5/dmm048940