Deep sequencing of the gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of variants
The TP53 gene remains the most frequently altered gene in human cancer, of which variants are associated with cancer risk, therapy resistance, and poor prognosis in several tumor types. To determine the true prognostic value of TP53 variants in non–small cell lung cancer, this study conducted furthe...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-02-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317694327 |