Interleukin 32 expression in human melanoma

Interleukin 32 expression in human melanoma

Abstract Background Various proinflammatory cytokines can be detected within the melanoma tumor microenvironment. Interleukin 32 (IL32) is produced by T cells, NK cells and monocytes/macrophages, but also by a subset of melanoma cells. We sought to better understand the biology of IL32 in human mela...

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Bibliographic Details
Main Authors: Helicia Paz, Jennifer Tsoi, Anusha Kalbasi, Catherine S. Grasso, William H. McBride, Dörthe Schaue, Lisa H. Butterfield, Deena M. Maurer, Antoni Ribas, Thomas G. Graeber, James S. Economou
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Interleukin 32 (IL32)
Melanoma dedifferentiation
IL32 transcriptional regulation
Immune infiltration
Myeloid polarization
Online Access:http://link.springer.com/article/10.1186/s12967-019-1862-y

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http://link.springer.com/article/10.1186/s12967-019-1862-y

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