Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma

Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma

Intra-tumour heterogeneity is the molecular hallmark of renal cancer, and the molecular tumour composition determines the treatment outcome of renal cancer patients. In renal cancer tumourigenesis, in general, different tumour clones evolve over time. We analysed intra-tumour heterogeneity and subcl...

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Bibliographic Details
Main Authors: Ariane L. Moore, Aashil A. Batavia, Jack Kuipers, Jochen Singer, Elodie Burcklen, Peter Schraml, Christian Beisel, Holger Moch, Niko Beerenwinkel
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
intra-tumour heterogeneity
private mutations
clonal exclusivity
Online Access:https://www.mdpi.com/2072-6694/13/9/2163

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https://www.mdpi.com/2072-6694/13/9/2163

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