Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

Beta3-adrenergic receptor signaling regulates adipose tissue browning. Here, the authors show that barr2 regulates internalization of beta3-adrenergic receptors and that mice lacking barr2 in adipocytes are protected from diet-induced weight gain and metabolic complications.

Bibliographic Details
Main Authors: Sai P. Pydi, Shanu Jain, Wesley Tung, Yinghong Cui, Lu Zhu, Wataru Sakamoto, Shalini Jain, Brent S. Abel, Monica C. Skarulis, Jie Liu, Thanh Huynh, Karel Pacak, Marc G. Caron, Oksana Gavrilova, Toren Finkel, Jürgen Wess
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11003-4

Internet

https://doi.org/10.1038/s41467-019-11003-4

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