Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease

Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease

Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T cells in controlling CHIKV infection and disease...

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Bibliographic Details
Main Authors: Rebecca M. Broeckel, Nicole Haese, Takeshi Ando, Igor Dmitriev, Craig N. Kreklywich, John Powers, Michael Denton, Patricia Smith, Thomas E. Morrison, Mark Heise, Victor DeFilippis, Ilhem Messaoudi, David T. Curiel, Daniel N. Streblow
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Chikungunya virus (CHIKV)
vaccine
T cell
pathogenesis
cytokine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02563/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02563/full

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