A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

Objective: Natural sources of molecular diversity remain of utmost importance as a reservoir of proteins and peptides with unique biological functions. We recently identified such a family of viral insulin-like peptides (VILPs). We sought to advance the chemical methods in synthesis to explore the s...

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Bibliographic Details
Main Authors: Fa Zhang, Emrah Altindis, C. Ronald Kahn, Richard D. DiMarchi, Vasily Gelfanov
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001630