Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function

Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function

The concentrative power of the transporters for dopamine (DAT), norepinephrine (NET), and serotonin (SERT) is thought to be fueled by the transmembrane Na+ gradient, but it is conceivable that they can also tap other energy sources, for example, membrane voltage and/or the transmembrane K+ gradient....

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Bibliographic Details
Main Authors: Shreyas Bhat, Marco Niello, Klaus Schicker, Christian Pifl, Harald H Sitte, Michael Freissmuth, Walter Sandtner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
dopamine transporter
serotonin transporter
norepinephrine transporter
intracellular potassium
Online Access:https://elifesciences.org/articles/67996

Internet

https://elifesciences.org/articles/67996

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