EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin

The pathogenic bacteria Clostridium difficile, Clostridium perfringens and Clostridium botulinum produce the binary actin ADP-ribosylating toxins CDT, iota and C2, respectively. These toxins are composed of a transport component (B) and a separate enzyme component (A). When both components assemble...

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Bibliographic Details
Main Authors: Leonie Schnell, Ann-Katrin Mittler, Mirko Sadi, Michel R. Popoff, Carsten Schwan, Klaus Aktories, Andrea Mattarei, Domenico Azarnia Tehran, Cesare Montecucco, Holger Barth
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Toxins
Subjects:
EGA
Online Access:http://www.mdpi.com/2072-6651/8/4/101