FGF21 requires βklotho to act in vivo.

FGF21 has gradually become a focal point in metabolic research given its intriguing and complex biology and relevance to drug discovery. Despite the large amount of accumulated data, there remains a dearth of understanding of FGF21 physiology at the molecular/whole organism level. The scaffold prote...

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Bibliographic Details
Main Authors: Andrew C Adams, Christine C Cheng, Tamer Coskun, Alexei Kharitonenkov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507945?pdf=render