Integrated functional, gene expression and genomic analysis for the identification of cancer targets.

Integrated functional, gene expression and genomic analysis for the identification of cancer targets.

The majority of new drug approvals for cancer are based on existing therapeutic targets. One approach to the identification of novel targets is to perform high-throughput RNA interference (RNAi) cellular viability screens. We describe a novel approach combining RNAi screening in multiple cell lines...

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Bibliographic Details
Main Authors: Elizabeth Iorns, Christopher J Lord, Anita Grigoriadis, Sarah McDonald, Kerry Fenwick, Alan Mackay, Charles A Mein, Rachael Natrajan, Kay Savage, Narinder Tamber, Jorge S Reis-Filho, Nicholas C Turner, Alan Ashworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19357772/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19357772/?tool=EBI

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