Mitochondrial dysfunction remodels one-carbon metabolism in human cells

Mitochondrial dysfunction is associated with a spectrum of human disorders, ranging from rare, inborn errors of metabolism to common, age-associated diseases such as neurodegeneration. How these lesions give rise to diverse pathology is not well understood, partly because their proximal consequences...

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Bibliographic Details
Main Authors: Bao, Xiaoyan Robert (Author), Ong, Shao-En (Author), Goldberger, Olga (Author), Peng, Jun (Author), Sharma, Rohit (Author), Thompson, Dawn A (Author), Vafai, Scott B (Author), Cox, Andrew G (Author), Marutani, Eizo (Author), Ichinose, Fumito (Author), Goessling, Wolfram (Author), Carr, Steven A (Author), Clish, Clary B (Author), Mootha, Vamsi K (Author), Regev, Aviv (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2016-12-02T16:27:58Z.
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