Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML
Leukemia stem cells (LSCs) have the capacity to self-renew and propagate disease upon serial transplantation in animal models, and elimination of this cell population is required for curative therapies. Here, we describe a series of pooled, in vivo RNAi screens to identify essential transcription fa...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-07-03T14:49:58Z.
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Subjects: | |
Online Access: | Get fulltext |