High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

Heat-shock factor 1 (HSF1) is the master transcriptional regulator of the cellular response to heat and a wide variety of other stressors. We previously reported that HSF1 promotes the survival and proliferation of malignant cells. At this time, however, the clinical and prognostic significance of H...

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Main Authors: Santagata, Sandro (Author), Mendillo, Marc L. (Author), Whitesell, Luke (Author), Lindquist, Susan (Contributor), Hu, Rong (Author), Lin, Nancy U. (Author), Collins, Laura C. (Author), Hankinson, Susan E. (Author), Schnitt, Stuart J. (Author), Tamimi, Rulla M. (Author), Ince, Tan A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2012-10-18T17:51:55Z.
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