Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Without therapy, most people infected with human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals ('elite controllers') maintain very low levels of HIV RNA without therapy, thereby making disease progression and transmission unlikely. Certain HLA class I alleles a...

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Main Authors: Kosmrlj, Andrej (Contributor), Read, Elizabeth L. (Contributor), Qi, Ying (Author), Allen, Todd M. (Contributor), Altfeld, Marcus (Contributor), Deeks, Steven G. (Author), Pereyra, Florencia (Contributor), Carrington, Mary (Contributor), Walker, Bruce D. (Contributor), Chakraborty, Arup K (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Chakraborty, Arup K. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2013-03-21T15:22:29Z.
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