Stochastic effects are important in intrahost HIV evolution even when viral loads are high

Stochastic effects are important in intrahost HIV evolution even when viral loads are high

Blood plasma viral loads and the time to progress to AIDS differ widely among untreated HIV-infected humans. Although people with certain HLA (HLA-I) alleles are more likely to control HIV infections without therapy, the majority of such untreated individuals exhibit high viral loads and progress to...

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Bibliographic Details
Main Authors: Read, Elizabeth L. (Contributor), Tovo-Dwyer, Allison A. (Contributor), Chakraborty, Arup K (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Chakraborty, Arup K. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2013-05-07T15:58:38Z.
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