Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines

Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines

Cancer is an inflammatory disease of tissue that is largely influenced by the interactions between multiple cell types, secreted factors, and signal transduction pathways. While single-cell sequencing continues to refine our understanding of the clonotypic heterogeneity within tumors, the complex in...

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Main Authors: Adalsteinsson, Viktor A. (Contributor), Tahirova, Narmin (Contributor), Tallapragada, Naren (Contributor), Yao, Xiaosai (Contributor), Campion, Liam (Author), Angelini, Alessandro (Contributor), Douce, Thomas B. (Contributor), Bowman, Brittany (Author), Williamson, Christina A. (Author), Huang, Cindy Y. (Contributor), Kwon, Douglas (Contributor), Wittrup, Karl Dane (Contributor), Love, John C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Love, J. Christopher (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2014-11-07T15:19:38Z.
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