Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers
Upon natural infection with pathogens or vaccination, antibodies are produced by a process called affinity maturation. As affinity maturation ensues, average affinity values between an antibody and ligand increase with time. Purified antibodies isolated from serum are invariably heterogeneous with r...
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Bibliographic Details
| Main Authors: |
Eisen, Ellen A.
(Author),
Eisen, Herman N.
(Contributor),
Kang, Myung Sun
(Contributor),
Eisen, Timothy Jonas
(Contributor),
Chakraborty, Arup K
(Author) |
|---|
| Other Authors: |
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
(Contributor),
Massachusetts Institute of Technology. Department of Biological Engineering
(Contributor),
Massachusetts Institute of Technology. Department of Biology
(Contributor),
Massachusetts Institute of Technology. Department of Chemical Engineering
(Contributor),
Massachusetts Institute of Technology. Department of Chemistry
(Contributor),
Massachusetts Institute of Technology. Department of Physics
(Contributor),
Ragon Institute of MGH, MIT and Harvard
(Contributor),
Whitehead Institute for Biomedical Research
(Contributor),
Koch Institute for Integrative Cancer Research at MIT
(Contributor),
Chakraborty, Arup K.
(Contributor) |
|---|
| Format: | Article
|
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| Language: | English |
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| Published: |
Public Library of Science,
2015-11-09T17:44:52Z.
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| Subjects: | |
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| Online Access: | Get fulltext
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