mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

by Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Sancak, Yasemin, Sabatini, David M., Wang, Shuyu, Ph. D. Massachusetts Institute of Technology
Published 2015

mTOR and cancer: many loops in one pathway

by Efeyan, Alejo, Sabatini, David
Published 2012

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma

by Sabatini, David, Wolfson, Rachel Laura, Efeyan, Alejo
Published 2017

Nutrient-sensing mechanisms and pathways

by Efeyan, Alejo, Comb, William C., Sabatini, David
Published 2015

Nutrients versus growth factors in mTORC1 activation

by Efeyan, Alejo, Sabatini, David M, Sabatini, David
Published 2015

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

by Laplante, Mathieu, Horvat, Simon, Festuccia, William T., Birsoy, Kivanc, Prevorsek, Zala, Efeyan, Alejo, Sabatini, David M, Sabatini, David
Published 2014

Amino acids and mTORC1: from lysosomes to disease

by Efeyan, Alejo, Zoncu, Roberto, Sabatini, David
Published 2017

Rag GTPase-mediated regulation of mTORC1 by nutrients is necessary for neonatal autophagy and survival

by Efeyan, Alejo, Zoncu, Roberto, Chang, Steven, Gumper, Iwona, Snitkin, Harriet, Kirak, Oktay, Sabatini, David D., Wolfson, Rachel Laura, Sabatini, David
Published 2015