Applications of the CRISPR-Cas9 system in cancer biology

by Sanchez-Rivera, Francisco Javier, Jacks, Tyler E.
Published 2018

Reply to Comment on "Sloppy models, parameter uncertainty, and the role of experimental design"

by Hagen, David Robert, Apgar, Joshua F., Witmer, David K., White, Forest M., Tidor, Bruce
Published 2013

Precision cancer mouse models through genome editing with CRISPR-Cas9

by Mou, Haiwei, Kennedy, Zachary, Yin, Hao, Xue, Wen, Anderson, Daniel Griffith
Published 2015

Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy

by Hill, Alison L., Selinger, Christian, Bershteyn, Anna, Craig, Morgan, Mo, Shirley S., Nikolic, Boris, Wood, Lowell, Eckhoff, Philip A., Nowak, Martin A., Kirtane, Ameya, Abouzid, Omar, Minahan Jr, Daniel J, Bensel, Taylor A, Mazdiyasni, Hormoz, Cleveland, Cody, Rogner, Jaimie L, Lee, Young-Ah, Booth, Lucas, Javid, Farhad, Wu, Sarah J., Grant, Tyler M, Bellinger, Andrew, Hayward, Alison M, Langer, Robert S, Traverso, Carlo Giovanni
Published 2018

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

by Novobrantseva, Tatiana I, Borodovsky, Anna, Wong, Jamie, Klebanov, Boris, Zafari, Mohammad, Yucius, Kristina, Querbes, William, Ge, Pei, Ruda, Vera M, Milstein, Stuart, Speciner, Lauren, Duncan, Rick, Barros, Scott, Basha, Genc, Cullis, Pieter, Akinc, Akin, Donahoe, Jessica S, Narayanannair Jayaprakash, K, Jayaraman, Muthusamy, Bogorad, Roman, Love, Kevin T, Whitehead, Kathryn Ann, Levins, Christopher G., Manoharan, Muthiah, Swirski, Filip K, Weissleder, Ralph, Langer, Robert S, Anderson, Daniel Griffith, de Fougerolles, Antonin, Nahrendorf, Matthias, Koteliansky, Victor
Published 2019

Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration

by Prahl, Louis S., Bangasser, Patrick F., Stopfer, Lauren Elizabeth, Hemmat, Mahya, White, Forest M., Rosenfeld, Steven S., Odde, David J.
Published 2020

Inactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancer

by Bronson, R T, Parisi, Tiziana, Lees, Jacqueline
Published 2016

Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

by Hamza, Bashar M., Ng, Sheng Rong, Prakadan, Sanjay, Delgado, Francisco Feijo, Chin, Christopher R., King, Emily M., Yang, Lucy F., Davidson, Shawn Michael, DeGouveia, Kelsey L., Cermak, Nathan, Warren Navia, Andrew, Winter, Peter S., Drake, Riley, Tammela, Tuomas, Li, Carman Man-Chung, Papagiannakopoulos, Thales, Gupta, Alejandro J., Shaw Bagnall, Josephine, Knudsen, Scott, Vander Heiden, Matthew G., Wasserman, Steven, Jacks, Tyler E, Shalek, Alexander K, Manalis, Scott R
Published 2020

Ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications

by Peng, Berney, Almeqdadi, Mohammad, Roper, Jatin, Yilmaz, Omer, Sokolov, Igor
Published 2020

In Vivo Systems Analysis Identifies Spatial and Temporal Aspects of the Modulation of TNF-α-Induced Apoptosis and Proliferation by MAPKs

by Lau, Ken S., Juchheim, Alwin M., Cavaliere, Kimberly R., Philips, Sarah R., Haigis, Kevin M., Lauffenburger, Douglas A
Published 2014

Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

by Cortez-Retamozo, Virna, Philips, Sarah R., Pittet, Mikael J., Haigis, Kevin M., Lau, Ken S., Lauffenburger, Douglas A
Published 2013

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

by Zhang, Yuan, Li, Na, Suh, Heikyung, Irvine, Darrell J
Published 2018

Development of a long-acting direct-acting antiviral system for hepatitis C virus treatment in swine

by Verma, Malvika, Chu, Jacqueline N, Salama, John Ashraf Fou, Faiz, Mohammed T., Eweje, Feyisope, Gwynne, Declan A, Lopes, Aaron C, Hess, Kaitlyn, Soares, Vance, Steiger, Christoph Winfried Johannes, McManus, Rebecca S, Koeppen, Ryan P., Hua, Tiffany P, Hayward, Alison M, Collins, Joy E, Tamang, Siddartha M, Ishida, Keiko, Miller, Jonathan B., Katz, Stephanie, Slocum, Alexander H, Sulkowski, Mark S., Thomas, David L., Langer, Robert S, Traverso, Carlo Giovanni
Published 2020

High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network

by Dittmann, Antje, Soltero, Nina L., Morshed, Nader, Mana, Mana, Yilmaz, Omer H., White, Forest M.
Published 2020

A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways

by Morton, Stephen Winford, Lee, Michael J., Deng, Zhou J., Siouve, Elise, Shopsowitz, Kevin, Shah, Nisarg J., Dreaden, Erik, Yaffe, Michael B, Hammond, Paula T
Published 2014

Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy

by Kwong, Brandon, Liu, Haipeng, Irvine, Darrell J
Published 2015

Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

by Deng, Zhou J., Morton, Stephen Winford, Ben-Akiva, Elana, Shopsowitz, Kevin, Hammond, Paula T, Dreaden, Erik
Published 2016

Metabolomics Investigation Reveals Metabolite Mediators Associated with Acute Lung Injury and Repair in a Murine Model of Influenza Pneumonia

by Cui, Liang, Zheng, Dahai, Lee, Yie Hou, Chan, Tze Khee, Kumar, Yadunanda, Ho, Wanxing Eugene, Ong, Choon Nam, Chen, Jianzhu, Tannenbaum, Steven R
Published 2017

Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity

by Kwong, Brandon, Gai, S. Annie, Elkhader, Jamal, Wittrup, Karl Dane, Irvine, Darrell J
Published 2014

A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non-Small Cell Lung Cancer

by Gu, Li, Deng, Zhou J., Roy, Sweta, Hammond, Paula T
Published 2021