Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

by Tekin, Halil, Simmons, Sean, Cummings, Beryl, Gao, Linyi, Adiconis, Xian, Hession, Cynthia C., Ghoshal, Ayan, Dionne, Danielle, Choudhury, Sourav, Yesilyurt, Volkan, Sanjana, Neville E, Shi, Xi, Lu, Congyi, Heidenreich, Matthias, Pan, Jen Q., Levin, Joshua Z., Zhang, Feng
Published 2020

Predicting cancer drug mechanisms of action using molecular network signatures

by Pritchard, Justin R., Bruno, Peter Michael, Hemann, Michael, Lauffenburger, Douglas A
Published 2014

PEG-Polypeptide Block Copolymers as pH-Responsive Endosome-Solubilizing Drug Nanocarriers

by Morton, Stephen Winford, Deng, Zhou J., Murphy, Ryan P., Epps, Thomas H., Quadir, Mohiuddin Abdul, Shopsowitz, Kevin, Hammond, Paula T
Published 2015

Microfluidic platform for characterizing TCR-pMHC interactions

by Stockslager, Max Andrew, Hecht, Vivian Chaya, Hu, Kevin, Aranda-Michel, Edgar C., Kimmerling, Robert John, Manalis, Scott R, Shaw, Josephine, Payer, Kristofor Robert
Published 2019

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

by Zhao, Boyang, Srinivas, Raja Ram, Creixell Morera, Pau, Tidor, Bruce, Lauffenburger, Douglas A, Hemann, Michael, Pritchard, Justin R.
Published 2017

Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations

by Sun, Daphne S., Dalin, Simona, Hemann, Michael, Lauffenburger, Douglas A, Zhao, Boyang
Published 2017

CD8[superscript +] T-cell Responses Rapidly Select for Antigen-Negative Tumor Cells in the Prostate

by Bak, S. Peter G., Barnkob, Mike Stein, Wittrup, Karl Dane, Chen, Jianzhu
Published 2014

Recognition of heparan sulfate by clinical strains of dengue virus serotype 1 using recombinant subviral particles

by Artpradit, Charlermchai, Gavrilov, Boris K., Rurak, Troy T., Ruchirawat, Mathuros, Sasisekharan, Ram, Robinson, Luke Nathaniel
Published 2014

Enhanced Stability of Polymeric Micelles Based on Postfunctionalized Poly(ethylene glycol)-b-poly(γ-propargyl l-glutamate): The Substituent Effect

by Zhao, Xiaoyong, Poon, Zhiyong, Engler, Amanda C., Bonner, Daniel K., Hammond, Paula T
Published 2013

Rapid assessment of T-cell receptor specificity of the immune repertoire

by Lin, Xingcheng, George, Jason T., Schafer, Nicholas P., Ng Chau, Kevin, Birnbaum, Michael E, Clementi, Cecilia, Onuchic, José N., Levine, Herbert
Published 2021

Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

by Luna, Joseph M., Hoffmann, Hans.-Heinrich, Espiritu, Christine, Sheahan, Timothy P., Rice, Charles M., Ramanan, Vyas, Trehan, Kartik, Ong, Mei Lyn, Chandrasekar, Hamsika, Christine, Kathleen, van Oudenaarden, Alexander, Bhatia, Sangeeta N, Schwartz, Robert E.
Published 2017

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

by Morshed, Nader, Ralvenius, William, Nott, Alexander, Watson, Lauren Ashley, Rodriguez, Felicia H, Akay, Leyla Anne, Joughin, Brian Alan, Pao, Ping-Chieh, Penney, Jay, LaRocque, Lauren, Mastroeni, Diego, Tsai, Li‐Huei, White, Forest M.
Published 2021

Addressing Genetic Tumor Heterogeneity through Computationally Predictive Combination Therapy

by Zhao, Boyang, Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A
Published 2014

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

by Szucs, Matthew J, Ammendolia, Dustin A, MacMullan, Melanie A, Rakoff-Nahoum, Seth, Mead, Benjamin Elliott, Ordovas-Montanes, Jose Manuel, Braun, Alexandra Provost, Levy, Lauren, Saluja, Prerna Bhargava, Yin, Xiaolei, Hughes, Travis K., Wadsworth, Marc Havens, Ahmad, Rushdy, Carr, Steven A, Langer, Robert S, Collins, James J., Shalek, Alexander K, Karp, Jeffrey Michael
Published 2018

MicroRNAs can generate thresholds in target gene expression

by Mukherji, Shankar, Ebert, Margaret S., Sharp, Phillip A., van Oudenaarden, Alexander, Tsang, John S., Zheng, Xinying Grace
Published 2012

Selective Mitogen Activated Protein Kinase Activity Sensors through the Application of Directionally Programmable D Domain Motifs

by Peterson, Laura B, Yaffe, Michael B, Imperiali, Barbara
Published 2016

Painting blood vessels and atherosclerotic plaques with an adhesive drug depot

by Kastrup, Christian, Nahrendorf, Matthias, Figueiredo, Jose Luiz, Lee, Haeshin, Kambhampati, Swetha, Lee, Timothy, Cho, Seung Woo, Gorbatov, Rostic, Iwamoto, Yoshiko, Dang, Tram T., Dutta, Partha, Yeon, Ju Hun, Cheng, Hao, Vegas, Arturo, Siegel, Cory D., MacDougall, Samantha, Okonkwo, Michael E., Thai, Anh, Stone, James R., Coury, Arthur J., Weissleder, Ralph, Langer, Robert, Anderson, Daniel Griffith, Pritchard, Christopher D., (Christopher David)
Published 2013

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

by Miraldi, Emily Rae, Sharfi, Hadar, Friedline, Randall H., Johnson, Hannah, Zhang, Tejia, Lau, Ken S., Ko, Hwi Jin, Curran, Timothy G., Haigis, Kevin M., Yaffe, Michael B., Bonneau, Richard, Lauffenburger, Douglas A., Kahn, Barbara B., Kim, Jason K., Neel, Benjamin G., Saghatelian, Alan, White, Forest M.
Published 2014

A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarray...

by Celiz, Adam D., Rajamohan, Divya, Davies, Martyn C., Alexander, Morgan R., Denning, Chris, Patel, Asha, Anderson, Daniel Griffith, Langer, Robert S
Published 2016

An EMT-Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

by Shapiro, Irina M., Flytzanis, Nicholas C., Balsamo, Michele, Condeelis, John S., Oktay, Maja H., Gertler, Frank, Cheng, Albert Wu, Burge, Christopher B
Published 2011