Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways

by Khurana, Vikram, Chung, Chee Yeun, Auluck, Pavan K., Fanning, Saranna, Tardiff, Daniel F., Bartels, Theresa, Eichhorn, Stephen W., Benyamini, Hadar, Lou, Yali, Nutter-Upham, Andy, Baru, Valeriya, Freyzon, Yelena, Costanzo, Michael, San Luis, Bryan-Joseph, Schöndorf, David C., Barrasa, M. Inmaculada, Ehsani, Sepehr, Sanjana, Neville, Zhong, Quan, Gasser, Thomas, Bartel, David P., Vidal, Marc, Deleidi, Michela, Boone, Charles, Berger, Bonnie, Lindquist, Susan, Peng, Jian, Koeva, Martina I, Tuncbag, Nurcan, Fraenkel, Ernest
Published 2018

SIRT2 Ablation Has No Effect on Tubulin Acetylation in Brain, Cholesterol Biosynthesis or the Progression of Huntington's Disease Phenotypes In Vivo

by Bobrowska, Anna, Donmez Yalcin, Gizem, Weiss, Andreas, Guarente, Leonard Pershing, Bates, Gillian P.
Published 2012

Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease

by He, Liang, Loika, Yury, Park, Yongjin, Bennett, David A, Kellis, Manolis, Kulminski, Alexander M
Published 2022

Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats

by Cantuti-Castelvetri, Ippolita, Keller-McGandy, Christine E., Kett, Lauren R., Landy, Alex, Hollingsworth, Zane R., Saka, Esen, Crittenden, Jill R., Nillni, Eduardo A., Young, Anne B., Standaert, David G., Graybiel, Ann M., F. Hernandez, Ledia
Published 2011

Optimizing deep brain stimulation settings using wearable sensing technology

by Patel, Shyamal, Mancinelli, Chiara, Hughes, Richard, Dalton, Anthony, Shih, Ludy, Bonato, Paolo
Published 2010

Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity

Published 2019

Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity

by Chen, Ying-Chou, Farzadfard, Fahim, Gharaei, Nava, Chen, William C. W., Cao, Jicong, Lu, Timothy K
Published 2021

Bursts of beta oscillation differentiate postperformance activity in the striatum and motor cortex of monkeys performing movement tasks

by Feingold, Joseph, Gibson, Daniel J., DePasquale, Brian, Graybiel, Ann M.
Published 2016

Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments

by Crittenden, Jill R., Graybiel, Ann M.
Published 2012

Rapid Selection of Cyclic Peptides that Reduce Alpha-Synuclein Toxicity in Yeast and Animal Models

by Lindquist, Susan, Caldwell, Guy A., Caldwell, Kim A., Naumann, Todd A., Santagata, Sandro, McCaffery, J. Michael, Hamamichi, Shusei, Kritzer, Joshua A.
Published 2010

SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

by Donmez Yalcin, Gizem, Arun, Anirudh, Chung, Chee Yeun, McLean, Pamela J., Lindquist, Susan, Guarente, Leonard Pershing
Published 2012

Automated Quality Control for Sensor Based Symptom Measurement Performed Outside the Lab

by Badawy, Reham, Raykov, Yordan P., Evers, Luc J. W., Bloem, Bastiaan R., Faber, Marjan J., Zhan, Andong, Claes, Kasper, Raykov, Yordan, Evers, Luc, Bloem, Bastiaan, Faber, Marjan, Little, Max
Published 2018

Selective Effects of Dopamine Depletion and L-DOPA Therapy on Learning-Related Firing Dynamics of Striatal Neurons

by Hernandez, Ledia F., Kubota, Yasuo, Hu, Dan, Howe, Mark William, Lemaire, Nune, Graybiel, Ann M.
Published 2013

Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA

by Lemaire, Nune, Ledia, F. Hernandez, Hu, Dan, Kubota, Yasuo, Howe, Mark William, Graybiel, Ann M.
Published 2013

Chronic multi-modal monitoring of neural activity in rodents and primates

by Schwerdt, Helen N, Gibson, Dan J, Amemori, Kenichi, Stanwicks, Lauren L, Yoshida, Tomoko, Cima, Michael J, Graybiel, Ann M
Published 2021

Chronic multi-modal monitoring of neural activity in rodents and primates

by Schwerdt, Helen, Gibson, Daniel J., Amemori, Ken-ichi, Stanwicks, Lauren L, Yoshida, Tomoko, Cima, Michael J., Graybiel, Ann M
Published 2022

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

by Heiman, Myriam, Heilbut, Adrian, Francardo, Veronica, Kulicke, Ruth, Fenster, Robert, Kolaczyk, Eric D., Mesirov, Jill P., Surmeier, Dalton J., Cenci, M. Angela, Greengard, Paul
Published 2014

Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication

by Flierl, Adrian, Oliveira, Luís M. A., Falomir-Lockhart, Lisandro J., Mak, Sally K., Hesley, Jayne, Soldner, Frank, Arndt-Jovin, Donna J., Jaenisch, Rudolf, Langston, J. William, Jovin, Thomas M., Schüle, Birgitt
Published 2014

Carnelian uncovers hidden functional patterns across diverse study populations from whole metagenome sequencing reads

by Nazeen, Sumaiya, Yu, Yun W, Berger Leighton, Bonnie
Published 2020

Context Dependent Neuroprotective Properties of Prion Protein (Prp)

by Steele, Andrew D., Lindquist, Susan, Jackson, Walker S., Auluck, Pavan K., Zhu, Chunni, Zhou, Zhipeng, Moskowitz, Michael A., Chesselet, Marie-Francoise
Published 2011