Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes

by Peiman Shooshtarizadeh, Anne Helness, Charles Vadnais, Nelleke Brouwer, Hugues Beauchemin, Riyan Chen, Halil Bagci, Frank J. T. Staal, Jean-François Coté, Tarik Möröy
Published 2019-03-01

A licensing step links AID to transcription elongation for mutagenesis in B cells

by Stephen P. Methot, Ludivine C. Litzler, Poorani Ganesh Subramani, Anil K. Eranki, Heather Fifield, Anne-Marie Patenaude, Julian C. Gilmore, Gabriel E. Santiago, Halil Bagci, Jean-François Côté, Mani Larijani, Ramiro E. Verdun, Javier M. Di Noia
Published 2018-03-01

Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

by Alexandre Mayran, Kevin Sochodolsky, Konstantin Khetchoumian, Juliette Harris, Yves Gauthier, Amandine Bemmo, Aurelio Balsalobre, Jacques Drouin
Published 2019-08-01

Phase separation by the polyhomeotic sterile alpha motif compartmentalizes Polycomb Group proteins and enhances their activity

by Elias Seif, Jin Joo Kang, Charles Sasseville, Olga Senkovich, Alexander Kaltashov, Elodie L. Boulier, Ibani Kapur, Chongwoo A. Kim, Nicole J. Francis
Published 2020-11-01

Post-Transcriptional Modulation of αENaC mRNA in Alveolar Epithelial Cells: Involvement of its 3’ Untranslated Region

by Francis Migneault, Frédéric Gagnon, Mihai Pascariu, Jonathan Laperle, Antoine Roy, André Dagenais, Yves Berthiaume
Published 2019-04-01

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

by Philippe Cloutier, Christian Poitras, Mathieu Durand, Omid Hekmat, Émilie Fiola-Masson, Annie Bouchard, Denis Faubert, Benoit Chabot, Benoit Coulombe
Published 2017-05-01

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α

by Yuko Tanabe, Yusuke Naito, Cristina Vasuta, Alfred Kihoon Lee, Youssouf Soumounou, Michael W. Linhoff, Hideto Takahashi
Published 2017-09-01

PRMT5 is essential for B cell development and germinal center dynamics

by Ludivine C. Litzler, Astrid Zahn, Alexandre P. Meli, Steven Hébert, Anne-Marie Patenaude, Stephen P. Methot, Adrien Sprumont, Thérence Bois, Daisuke Kitamura, Santiago Costantino, Irah L. King, Claudia L. Kleinman, Stéphane Richard, Javier M. Di Noia
Published 2019-01-01

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

by Noumeira Hamoud, Viviane Tran, Takahiro Aimi, Wataru Kakegawa, Sylvie Lahaie, Marie-Pier Thibault, Ariane Pelletier, G. William Wong, In-San Kim, Artur Kania, Michisuke Yuzaki, Michel Bouvier, Jean-François Côté
Published 2018-10-01

HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

by Ines Desanlis, Yacine Kherdjemil, Alexandre Mayran, Yasser Bouklouch, Claudia Gentile, Rushikesh Sheth, Rolf Zeller, Jacques Drouin, Marie Kmita
Published 2020-05-01

PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

by Mélissa Léveillé, Aurèle Besse-Patin, Nathalie Jouvet, Aysim Gunes, Sarah Sczelecki, Stewart Jeromson, Naveen P. Khan, Cindy Baldwin, Annie Dumouchel, Jorge C. Correia, Paulo R. Jannig, Jonathan Boulais, Jorge L. Ruas, Jennifer L. Estall
Published 2020-04-01

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2

by Célia Alecki, Victoria Chiwara, Lionel A. Sanz, Daniel Grau, Osvaldo Arias Pérez, Elodie L. Boulier, Karim-Jean Armache, Frédéric Chédin, Nicole J. Francis
Published 2020-04-01

Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila

by Julie Bergalet, Dhara Patel, Félix Legendre, Catherine Lapointe, Louis Philip Benoit Bouvrette, Ashley Chin, Mathieu Blanchette, Eunjeong Kwon, Eric Lécuyer
Published 2020-03-01

OA2-4 Enhancing HIV-1 virion tethering by BST2/tetherin sensitizes productively and latently infected T cells to ADCC mediated by broadly neutralizing anti-HIV antibodies

by T.N.Q. Pham, S. Lukhele, É.A. Cohen
Published 2016-07-01

POS-432 DELETION OF THE POLYCYSTIN-1 COILED-COIL MOTIF LEADS TO A SEVERE FUNCTIONAL HYPOMORPHIC ADPKD ALLELE IN MICE: INSIGHTS INTO INTRACELLULAR MECHANISMS

by M.L. PAUL, A. Kurbegovic, M. Trudel
Published 2021-04-01

Low density lipoprotein delays clearance of triglyceride-rich lipoprotein by human subcutaneous adipose tissue

by Simon Bissonnette, Huda Salem, Hanny Wassef, Nathalie Saint-Pierre, Annie Tardif, Alexis Baass, Robert Dufour, May Faraj
Published 2013-05-01

Data for the generation of RNA spatiotemporal distributions and interpretation of Chk1 and SLBP protein depletion phenotypes during Drosophila embryogenesis

by Fabio Alexis Lefebvre, Louis Philip Benoit Bouvrette, Julie Bergalet, Eric Lécuyer
Published 2017-08-01

POS-433 MODELING PKD1 TARGETING STRATEGIES IN A PKD1 LOSS-OF-FUNCTION MOUSE MODEL

by L. PERRON, A. Kurbegovic, K. Loayza, C. Pacis, M. Trudel
Published 2021-04-01

Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

by Konstantin Khetchoumian, Aurélio Balsalobre, Alexandre Mayran, Helen Christian, Valérie Chénard, Julie St-Pierre, Jacques Drouin
Published 2019-09-01

Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface‐expression of LDLR and CD36 and NLRP3 inflammasome

by Yannick Cyr, Valérie Lamantia, Simon Bissonnette, Melanie Burnette, Aurèle Besse‐Patin, Annie Demers, Martin Wabitsch, Michel Chrétien, Gaétan Mayer, Jennifer L. Estall, Maya Saleh, May Faraj
Published 2021-02-01