Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ

by Edward H. Leiter, Marjorie Strobel, Adam O'Neill, David Schultz, Andrew Schile, Peter C. Reifsnyder
Published 2013-01-01

Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis

by Jethro S. Johnson, Daniel J. Spakowicz, Bo-Young Hong, Lauren M. Petersen, Patrick Demkowicz, Lei Chen, Shana R. Leopold, Blake M. Hanson, Hanako O. Agresta, Mark Gerstein, Erica Sodergren, George M. Weinstock
Published 2019-11-01

FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods

by Timothy Becker, Wan-Ping Lee, Joseph Leone, Qihui Zhu, Chengsheng Zhang, Silvia Liu, Jack Sargent, Kritika Shanker, Adam Mil-homens, Eliza Cerveira, Mallory Ryan, Jane Cha, Fabio C. P. Navarro, Timur Galeev, Mark Gerstein, Ryan E. Mills, Dong-Guk Shin, Charles Lee, Ankit Malhotra
Published 2018-03-01

Sexual-dimorphism in human immune system aging

by Eladio J. Márquez, Cheng-han Chung, Radu Marches, Robert J. Rossi, Djamel Nehar-Belaid, Alper Eroglu, David J. Mellert, George A. Kuchel, Jacques Banchereau, Duygu Ucar
Published 2020-02-01

Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines

by Xing Yi Woo, Anuj Srivastava, Joel H. Graber, Vinod Yadav, Vishal Kumar Sarsani, Al Simons, Glen Beane, Stephen Grubb, Guruprasad Ananda, Rangjiao Liu, Grace Stafford, Jeffrey H. Chuang, Susan D. Airhart, R. Krishna Murthy Karuturi, Joshy George, Carol J. Bult
Published 2019-07-01

Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data

by Haitham Ashoor, Xiaowen Chen, Wojciech Rosikiewicz, Jiahui Wang, Albert Cheng, Ping Wang, Yijun Ruan, Sheng Li
Published 2020-03-01

Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells

by Joshy George, Asli Uyar, Kira Young, Lauren Kuffler, Kaiden Waldron-Francis, Eladio Marquez, Duygu Ucar, Jennifer J. Trowbridge
Published 2016-07-01

Chromatin topology reorganization and transcription repression by PML-RARα in acute promyeloid leukemia

by Ping Wang, Zhonghui Tang, Byoungkoo Lee, Jacqueline Jufen Zhu, Liuyang Cai, Przemyslaw Szalaj, Simon Zhongyuan Tian, Meizhen Zheng, Dariusz Plewczynski, Xiaoan Ruan, Edison T. Liu, Chia-Lin Wei, Yijun Ruan
Published 2020-05-01

Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status

by Peishan Li, Ming Lu, Jiayuan Shi, Li Hua, Zheng Gong, Qing Li, Leonard D. Shultz, Guangwen Ren
Published 2020-09-01

Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

by Shubham Khetan, Susan Kales, Romy Kursawe, Alexandria Jillette, Jacob C. Ulirsch, Steven K. Reilly, Duygu Ucar, Ryan Tewhey, Michael L. Stitzel
Published 2021-09-01

Mouse Genome Informatics: Mapping/Homology Data

by D. Bradt, C.J. Bult, J.A. Blake, J.A. Kadin, J.E. Richardson, J.T. Eppig
Published 2002-01-01

AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data

by Asa Thibodeau, Alper Eroglu, Christopher S. McGinnis, Nathan Lawlor, Djamel Nehar-Belaid, Romy Kursawe, Radu Marches, Daniel N. Conrad, George A. Kuchel, Zev J. Gartner, Jacques Banchereau, Michael L. Stitzel, A. Ercument Cicek, Duygu Ucar
Published 2021-09-01

CRISPR artificial splicing factors

by Menghan Du, Nathaniel Jillette, Jacqueline Jufen Zhu, Sheng Li, Albert Wu Cheng
Published 2020-06-01

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

by Aziz Taghbalout, Menghan Du, Nathaniel Jillette, Wojciech Rosikiewicz, Abhijit Rath, Christopher D. Heinen, Sheng Li, Albert W. Cheng
Published 2019-09-01

HBA-DEALS: accurate and simultaneous identification of differential expression and splicing using hierarchical Bayesian analysis

by Guy Karlebach, Peter Hansen, Diogo FT Veiga, Robin Steinhaus, Daniel Danis, Sheng Li, Olga Anczukow, Peter N Robinson
Published 2020-07-01

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

by Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Published 2020-04-01

Split selectable markers

by Nathaniel Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert Wu Cheng
Published 2019-10-01

epihet for intra-tumoral epigenetic heterogeneity analysis and visualization

by Xiaowen Chen, Haitham Ashoor, Ryan Musich, Jiahui Wang, Mingsheng Zhang, Chao Zhang, Mingyang Lu, Sheng Li
Published 2021-01-01

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

by Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, the MODEL-AD Consortium, Gregory W. Carter
Published 2020-11-01

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma

by Gareth R. Howell, Katharine H. MacNicoll, Catherine E. Braine, Ileana Soto, Danilo G. Macalinao, Gregory L. Sousa, Simon W.M. John
Published 2014-11-01