Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

by Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J. Patel, J. Fraser Glickman, Manuel Ascano
Published 2017-09-01

Sexually dimorphic and asymmetric effects of embryonic ethanol exposure on hypocretin/orexin neurons as related to behavioral changes in zebrafish

by Adam D. Collier, Nushrat Yasmin, Nailya Khalizova, Samantha Campbell, Amanda Onoichenco, Milisia Fam, Avi S. Albeg, Sarah F. Leibowitz
Published 2021-08-01

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

by Anirban Banerjee, Alice Lee, Ernest Campbell, Roderick MacKinnon
Published 2013-05-01

The Conserved RNA Exonuclease Rexo5 Is Required for 3′ End Maturation of 28S rRNA, 5S rRNA, and snoRNAs

by Stefanie Gerstberger, Cindy Meyer, Sigi Benjamin-Hong, Joe Rodriguez, Daniel Briskin, Claudia Bognanni, Kimberly Bogardus, Hermann Steller, Thomas Tuschl
Published 2017-10-01

Corrigendum to “Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression”[Mol Metab 4 (2015) 392–405]

by Yi-Hsueh Lu, Olof Stefan Dallner, Kivanc Birsoy, Gulya Fayzikhodjaeva, Jeffrey M. Friedman
Published 2015-08-01

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

by Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J. Patel, J. Fraser Glickman, Manuel Ascano
Published 2017-11-01

Structural basis for transcription complex disruption by the Mfd translocase

by Jin Young Kang, Eliza Llewellyn, James Chen, Paul Dominic B Olinares, Joshua Brewer, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Published 2021-01-01

Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks

by Lance D Langston, Ryan Mayle, Grant D Schauer, Olga Yurieva, Daniel Zhang, Nina Y Yao, Roxana E Georgescu, Mike E O'Donnell
Published 2017-09-01

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

by Roxana E Georgescu, Grant D Schauer, Nina Y Yao, Lance D Langston, Olga Yurieva, Dan Zhang, Jeff Finkelstein, Mike E O'Donnell
Published 2015-04-01

Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice

by P H Weinstock, C L Bisgaier, T Hayek, K Aalto-Setala, E Sehayek, L Wu, P Sheiffele, M Merkel, A D Essenburg, J L Breslow
Published 1997-09-01

Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females

by Elizabeth R. De Oliveira e Silva, Margaret Kong, Zhihua Han, Catherine Starr, Elizabeth M. Kass, Suh-Hang Hank Juo, David Foster, Hayes M. Dansky, Martin Merkel, Katherine Cundey, Eliot A. Brinton, Jan L. Breslow, Jonathan D. Smith
Published 1999-07-01

A limbic circuit selectively links active escape to food suppression

by Estefania P Azevedo, Bowen Tan, Lisa E Pomeranz, Violet Ivan, Robert Fetcho, Marc Schneeberger, Katherine R Doerig, Conor Liston, Jeffrey M Friedman, Sarah A Stern
Published 2020-09-01

FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

by Kirsty Sawicka, Caryn R Hale, Christopher Y Park, John J Fak, Jodi E Gresack, Sarah J Van Driesche, Jin Joo Kang, Jennifer C Darnell, Robert B Darnell
Published 2019-12-01

Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

by Byungchul Kim, Yen-Chih Wang, Charles W Hespen, Juliel Espinosa, Jeanne Salje, Kavita J Rangan, Deena A Oren, Jin Young Kang, Virginia A Pedicord, Howard C Hang
Published 2019-04-01

Epigenetic modulators of monocytic function: implication for steady state and disease in the CNS .

by F. Nina Papavasiliou, Youngcheul eChung, Khatuna eGagnidze, Kaitlyn H. Hajdarovic, Dan C. Cole, Karen eBulloch
Published 2016-01-01

Measuring in vivo protein turnover and exchange in yeast macromolecular assemblies

by Zhanna Hakhverdyan, Kelly R. Molloy, Roman I. Subbotin, Javier Fernandez-Martinez, Brian T. Chait, Michael P. Rout
Published 2021-09-01

APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA

by Jennifer A. Bohn, Keyur Thummar, Ashley York, Alice Raymond, W. Clay Brown, Paul D. Bieniasz, Theodora Hatziioannou, Janet L. Smith
Published 2017-10-01

A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates

by Jennifer R. Keeffe, Koen K.A. Van Rompay, Priscilla C. Olsen, Qiao Wang, Anna Gazumyan, Stephanie A. Azzopardi, Dennis Schaefer-Babajew, Yu E. Lee, Jackson B. Stuart, Anil Singapuri, Jennifer Watanabe, Jodie Usachenko, Amir Ardeshir, Mohsan Saeed, Marianna Agudelo, Thomas Eisenreich, Stylianos Bournazos, Thiago Y. Oliveira, Charles M. Rice, Lark L. Coffey, Margaret R. MacDonald, Pamela J. Bjorkman, Michel C. Nussenzweig, Davide F. Robbiani
Published 2018-11-01

Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

by Elizabeth A. Hubin, Mirjana Lilic, Seth A. Darst, Elizabeth A. Campbell
Published 2017-07-01

Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior

by J. Blaze, A. Navickas, H. L. Phillips, S. Heissel, A. Plaza-Jennings, S. Miglani, H. Asgharian, M. Foo, C. D. Katanski, C. P. Watkins, Z. T. Pennington, B. Javidfar, S. Espeso-Gil, B. Rostandy, H. Alwaseem, C. G. Hahn, H. Molina, D. J. Cai, T. Pan, W. D. Yao, H. Goodarzi, F. Haghighi, S. Akbarian
Published 2021-08-01