Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans

by Mizuki Kurashina, Jane Wang, Jeffrey Lin, Kathy Kyungeun Lee, Arpun Johal, Kota Mizumoto
Published 2021-08-01

Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation

by Hyeogsun Kwon, Mubasher Mohammed, Oscar Franzén, Johan Ankarklev, Ryan C Smith
Published 2021-07-01

Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway

by Hyae Yon Kweon, Mi-Ni Lee, Max Dorfel, Seungwoon Seo, Leah Gottlieb, Thomas PaPazyan, Nina McTiernan, Rasmus Ree, David Bolton, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J Conway, Taesoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Goo Taeg Oh, Gholson J Lyon
Published 2021-08-01

Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection

by Mackenzie M Shipley, Vidya Mangala Prasad, Laura E Doepker, Adam Dingens, Duncan K Ralph, Elias Harkins, Amrit Dhar, Dana Arenz, Vrasha Chohan, Haidyn Weight, Kishor Mandaliya, Jesse D Bloom, Frederick A Matsen IV, Kelly K Lee, Julie M Overbaugh
Published 2021-07-01

Different translation dynamics of β- and γ-actin regulates cell migration

by Pavan Vedula, Satoshi Kurosaka, Brittany MacTaggart, Qin Ni, Garegin Papoian, Yi Jiang, Dawei W Dong, Anna Kashina
Published 2021-06-01

Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration

by Ines Lahmann, Joscha Griger, Jie-Shin Chen, Yao Zhang, Markus Schuelke, Carmen Birchmeier
Published 2021-08-01

Variation in the modality of a yeast signaling pathway is mediated by a single regulator

by Julius Palme, Jue Wang, Michael Springer
Published 2021-08-01

Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

by S Jordan Kerns, Chaitra Belgur, Debora Petropolis, Marianne Kanellias, Riccardo Barrile, Johannes Sam, Tina Weinzierl, Tanja Fauti, Anne Freimoser-Grundschober, Jan Eckmann, Carina Hage, Martina Geiger, Patrick Ray Ng, William Tien-Street, Dimitris V Manatakis, Virginie Micallef, Regine Gerard, Michael Bscheider, Ekaterina Breous-Nystrom, Anneliese Schneider, Anna Maria Giusti, Cristina Bertinetti-Lapatki, Heather Shannon Grant, Adrian B Roth, Geraldine A Hamilton, Thomas Singer, Katia Karalis, Annie Moisan, Peter Bruenker, Christian Klein, Marina Bacac, Nikolce Gjorevski, Lauriane Cabon
Published 2021-08-01

Perception of microstimulation frequency in human somatosensory cortex

by Christopher L Hughes, Sharlene N Flesher, Jeffrey M Weiss, Michael Boninger, Jennifer L Collinger, Robert A Gaunt
Published 2021-07-01

Analysis of the mechanosensor channel functionality of TACAN

by Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Published 2021-08-01

TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

by Jing Xue, Yan Han, Hamid Baniasadi, Weizhong Zeng, Jimin Pei, Nick V Grishin, Junmei Wang, Benjamin P Tu, Youxing Jiang
Published 2021-08-01

GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

by Sequoyah Reynoso, Vanessa Castillo, Gajanan Dattatray Katkar, Inmaculada Lopez-Sanchez, Sahar Taheri, Celia Espinoza, Cristina Rohena, Debashis Sahoo, Pascal Gagneux, Pradipta Ghosh
Published 2021-08-01

Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

by Ryo Hatori, Brent M Wood, Guilherme Oliveira Barbosa, Thomas B Kornberg
Published 2021-07-01

Binocular rivalry reveals an out-of-equilibrium neural dynamics suited for decision-making

by Robin Cao, Alexander Pastukhov, Stepan Aleshin, Maurizio Mattia, Jochen Braun
Published 2021-08-01

Single caudate neurons encode temporally discounted value for formulating motivation for action

by Yukiko Hori, Koki Mimura, Yuji Nagai, Atsushi Fujimoto, Kei Oyama, Erika Kikuchi, Ken-ichi Inoue, Masahiko Takada, Tetsuya Suhara, Barry J Richmond, Takafumi Minamimoto
Published 2021-07-01

Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function

by Fiona Haward, Magdalena M Maslon, Patricia L Yeyati, Nicolas Bellora, Jan N Hansen, Stuart Aitken, Jennifer Lawson, Alex von Kriegsheim, Dagmar Wachten, Pleasantine Mill, Ian R Adams, Javier F Caceres
Published 2021-08-01

Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

by Jee Min Kim, Pat Visanpattanasin, Vivian Jou, Sheng Liu, Xiaona Tang, Qinsi Zheng, Kai Yu Li, Jonathan Snedeker, Luke D Lavis, Timothee Lionnet, Carl Wu
Published 2021-07-01

In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin

by Ben C Tilly, Gillian E Chalkley, Jan A van der Knaap, Yuri M Moshkin, Tsung Wai Kan, Dick HW Dekkers, Jeroen AA Demmers, C Peter Verrijzer
Published 2021-07-01

Molecular characterization of projection neuron subtypes in the mouse olfactory bulb

by Sara Zeppilli, Tobias Ackels, Robin Attey, Nell Klimpert, Kimberly D Ritola, Stefan Boeing, Anton Crombach, Andreas T Schaefer, Alexander Fleischmann
Published 2021-07-01

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

by Nikhil Faulkner, Kevin W Ng, Mary Y Wu, Ruth Harvey, Marios Margaritis, Stavroula Paraskevopoulou, Catherine Houlihan, Saira Hussain, Maria Greco, William Bolland, Scott Warchal, Judith Heaney, Hannah Rickman, Moria Spyer, Daniel Frampton, Matthew Byott, Tulio de Oliveira, Alex Sigal, Svend Kjaer, Charles Swanton, Sonia Gandhi, Rupert Beale, Steve J Gamblin, John W McCauley, Rodney Stuart Daniels, Michael Howell, David Bauer, Eleni Nastouli, George Kassiotis
Published 2021-07-01